Human Longevity’s Full Body Testing. Is it something you should consider?
Do you think you are healthy? How do you measure this? Today, it is possible to receive full body testing, also known as a comprehensive physical examination, as part of Setting Your Health Baseline. You can see if you are healthy and then use this baseline to track how your lifestyle changes improve or degrade your health.
Twenty years ago, full body testing was not recommended. The dangers of the tests and risks of false-positives outweighed medical sciences ability to cure what was found or prescribe preventative measures. That concern still exists today within mainstream medical practice. However, technological advancements have reduced the dangers of radiation exposure to safe levels and the detail which modern equipment can see the body has dramatically reduced the risk of false positives.
The biggest remaining modern issue is whether you want to know if you have a serious, undiagnosed medical or genetic condition, that may or may not be treatable. If you want to know or are curious about the experience, read on as we review the Human Longevity 100+ full body testing service.
Setting Your Health Baseline Part 2: The Human Longevity Institute's 100+ Experience
Craig Venter is regarded as one of the leading scientists of the 21st century, in particular for his work in sequencing the human genome. In pursuing his passion for human life extension, he co-founded Human Longevity Inc. (HLI). Although Dr. Venter is no longer affiliated with them, HLI provides proactive healthcare through comprehensive advanced full body screening and genetic analysis which they’ve branded as their 100+ program to assist you to live to over 100 years old.
Full body testing has been performed for over 1,000 clients and discovered clinically significant results in 40% of those with 14.4% requiring near-term or immediate follow-up. Study results included many other actionable findings.
100+ goes way beyond your mainstream annual physical testing. Full body testing covers:
- Full body cancer and tumor radiation-free MRI screening
- Neurologic diseases and brain disorders
- Aneurysm detection
- Proper organ structure and function (thyroid, kidney, liver, pancreas, prostate, uterus, ovaries, bladder)
- Colon cancer screening with Cologuard every 3 years.
- Proper cardiac structure and function along with heart monitoring using Apple Watch or Zio iRhythm
- Coronary calcium CT scan (every 5 years)
- DEXA bone density testing (every 3 years)
- Advanced blood (40+ biomarkers) and urine analysis via Quest Diagnostics
- HLI staff painlessly draw 12-14 vials of blood, which from the research of the Conboy Laboratory, provides unexpected additional health benefits
- Insulin sensitivity testing with FreeStyle Libre
- Body composition analysis with InBody 770 determining your percentages of body fat, muscle and water
- Genetic issues from whole genome sequencing analyzed along with your personal and family medical history
- 12 months of comprehensive 24×7 precision medicine primary care including same day acute care
- Personalized health and wellness longevity program recommendations including for exercise performance, nutrition, supplement and prescription medicines
- Specialty referrals and consultations with world-renowned Harvard Medical School and Massachusetts General Hospital physicians, when needed
100+ full body testing currently does not cover:
- GRAIL’s Galleri multi-cancer blood test (offered for $950 as a recommended add-on)
- Skin cancer detection
- Microbiome analysis
Human Longevity Full Body Test Equipment
HLI partners with GE and Siemens to develop and deliver advanced diagnostic technology such as Magnetic Resonance Imaging (MRI). MRI uses a powerful magnetic field, radio frequency pulses and a computer to produce detailed pictures of brains, organs, soft tissues, bone and virtually all other internal body structures. MRI does not use ionizing radiation (x-rays).
For body MRI scans, HLI uses the Siemens Magnetom Skyra scanner at their San Diego location and the Siemens Magnetom Vida in San Francisco. San Diego will upgrade to a Vida in 2024. You get to listen to Pandora and watch scenic nature videos while the machine beeps and whirs. Select your music wisely so the machine sounds blend in harmoniously. This takes about 1 hour including some controlled breathing during the last 15 minutes for additional accuracy.
For brain scans, HLI uses the GE Signa Premier 3 Tesla neuro solution. This takes about 20 minutes. The experience is similar to the body scan, but without the controlled breathing.
- The Computed Tomography (CT) test using GE Revolution CT equipment is a diagnostic imaging test used to create detailed images of internal organs, bones, soft tissue and blood vessels. The cross-sectional images generated during a CT scan can be reformatted in multiple planes, and can even generate three-dimensional images. CT scanning is often the best method for detecting many different cancers since the images allow your doctor to confirm the presence of a tumor and determine its size and location. CT is fast, painless, noninvasive and accurate. Radiation exposure is the equivalent of what you receive on a round-trip cross-country flight.
- A cardiac 4D ultrasound using the GE Vivid E95 Ultra Edition and electrocardiogram with the GE MAC2000. You can see your heart beating and your valves opening and closing rapidly. It is a very cool experience. From talking with the ultrasound technician, it is rare that they find issues, but when they do, they can save your life.
Human Longevity Full Body Testing Cost
Human Longevity’s 100+ program originally provided one-time full body testing for $25,000. As of 2024, the cost is $20,000 for one year with favorable savings for multi-year memberships. Insurance providers do not provide reimbursement for HLI services. The information gathered is kept private and you own it, but they do use your depersonalized data for their research. They are headquartered in San Diego and expanded to open a San Francisco facility. You can choose to share selective data with your primary care physician as you like.
So what does it feel like to go for a Human Longevity exam?
A few hours before your visit, it is normal to feel nervous, in part from the ten hour pre-visit fast, plus any time change from traveling to the West Coast. Your stomach may be jittery from hunger.
It is likely you will be wondering what flaws will be found. Given the comprehensive nature of the test, it would be surprising if nothing is uncovered. If issues are found, you hope there are modern treatments that are safe and worth doing. Although it might be upsetting to think about, if there are genetic issues, you wonder whether you will share those with family and relatives.
Writing notes on the experience is helpful to calm your thoughts and you will be very much looking forward to your next meal.
The visit requires advance scheduling and lasts about five hours. Once there, the Human Longevity building and staff make you feel comfortable. The building and the rooms are reminiscent of a luxury hotel. The HLI staff appear healthy and take good care of themselves.
Each patient gets their own private room with healthy snacks and new-age beverages such as Flow, Glow and Life Water. A tasty, fresh local food breakfast or lunch is provided after your blood draw is completed.
You go through a cycle of the various tests, each with a different medical specialist. Their stories on why they work there are fascinating. One would not likely be alive otherwise.
At the end of your visit, you meet with a staff physician to review some of your full body testing results. For example, you get to see your brain, heart, liver, kidneys and other internal organs and find our if there are any major concerns. If you see things you don’t like such as cardiac calcium in your heart or a high body fat percentile, you have strong motivators to change your diet. You receive your body composition report as well.
The Full Results:
After a couple weeks, full imaging, blood and urine results are provided within a secure portal and covered in detail during a 30 minute video call with your concierge precision-medicine physician.
After 6-7 weeks, genetic results are provided, combined with another friendly video conference call. The ~100 page genetic results report covers ancestral history, medically significant findings and a review of genes which respond to medications. For example, there can be a genetic risk to taking Warfarin (Coumadin) for those with the VKORC1 gene. There is an appropriate amount of explanation and detail. Not too much. Not too little. It is not surprising to have medically significant findings given ~20,000 protein-coding genes and ~1,600 known possible genetic diseases. There are only fifty genetic defects which are considered medically actionable. There are 4.0 to 4.3 million genetics variants per person.
Included in your genetic results is a section which focuses on health traits and risks. It turns out that lifestyle is much more a risk than genetics. More people need to know this. In discussions about lifespan and healthspan, the refrain is, “I’m relying on my genetics.” Unfortunately, life usually doesn’t work that way.
The 100+ exam exceeded expectations and is highly recommended. The pleasantly surprising result is knowing what conditions you do not have. Finding out things like you don’t have cancer and you didn’t seriously damage your liver in college (or at least it has fully repaired itself) are reassuring. There is tremendous comfort in peace of mind.
Seeing conditions you do have, like cardiac calcium, makes your personal health science real. It gives strong motivation to make changes such as following the American Heart Association’s dietary and lifestyle recommendations for preventing heart disease, the cause of 1 out of 3 deaths in the United States.
Also, knowing your genetic interaction with common medicines is important. They are useful to share with your primary care physician.
In Keep Health’s opinion, the likelihood of benefiting from extended healthspan and lifespan is worth more than the time and cost.